An Overview on Clinical Implications of Nanobacteria

Pathological calcification is becoming recognized as an important feature in the dynamics of a variety of diseases, such as renal stone, atherosclerosis, pulp stones, scleroderma and arthritis, etc. from which millions of human beings suffer in all ages. Nanobacterium sanguineum is the first calcium phosphate mineral containing nanoorganism isolated from human blood that causes pathological disease calcification in humans. Nanobacteria are the smallest cell-walled bacteria, recently discovered in human and cow blood and commercial cell culture serum. Here in the article controversy and critical role of calcifying nanoparticles as nidi and triggering factor in human pathologic calcifications are discussed.